Mouse tPA Genetically Deficient Spleen from Innovative Research is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Flash-frozen immediately upon removal.
Product Details:
- Species:Mouse
- Antigen:tPA
- Format:Frozen tissue
- Storage Conditions:-70 C
- Strain:C57BL6/SJL
- Chromosome:8
- Gene:PLAT
- Genomic TargetExon 4
- Mutation:16 base pair deletion
- Phenotype:Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA.
This product can be useful as a control in a wide range of in vitro applications, including ELISA and Western Blot, among others. Useful for research in cardiovascular and neurological studies.
Mouse Model Details
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